Healing Efficacy After Surgery and Intensity-Modulated Radiotherapy for Extremely Rare Maxillary Giant Cell Tumor

Abstract

Giant cell tumors are rare benign borderline tumors, and maxillary localization is extremely rare. Because of the few clinical cases, healing behavior is very different, although the primary is the surgery. We present a 72-year-old man in which, on the occasion of difficulty left nasal breathing with four months of length, in January 2021 an operation was carried out on a left maxillary sinus. Histological diagnosis is a giant cell tumor (GCT) of the maxillary sinus. The patient is targeted for post-operative radiotherapy (RT). After one month of surgery, an intensity-modulated RT (IMRT) by the VMAT metod in the tumor area in the left nasal cavity and the left maxillary sinus up to total dose (TD) 66 Gy, as well as a 5 mm zone in the surrounding healthy tissue (CTVp) up to TD 64 Gy with daily dose (DD) 2 Gy were performed. The main purpose of this article is to emphasize the difficult pathologist diagnosis, as well as presenting the healing capabilities of intensity- modulated radiotherapy (IMRT). In the central cranial and facial GCTs, due to the impossibility of carrying out radical surgery, a postoperative IMRT is imposed, which achieves a homogeneous distribution of the radical dose in the target volumes with simultaneously strict haircuts of surrounding healthy tissues and organs.