Gut Microbiota and Comprehensive Analysis of Drug Resistance Mechanisms in Tuberculosis

Abstract

Tuberculosis (TB) remains one of the most serious infectious diseases globally, and the emergence of drug-resistant strains has complicated treatment efforts significantly. In recent years, the gut microbiota, an essential component of the human microecosystem, has garnered widespread attention for its impact on various diseases, including tuberculosis. This review aims to explore the relationship between gut microbiota and drug resistance in TB, analyzing potential mechanisms and discussing the latest research findings in this field. By understanding the interplay between gut microbiota and mycobacterial resistance, we hope to shed light on novel therapeutic strategies and improve clinical outcomes for TB patients facing drug-resistant infections.