Pathogenetic Consequences of Prolonged Immobilization in Elderly and Senile Individuals and Modern Approaches to Restorative Treatment

Authors

  • Bon LI Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus Author
  • Znavets PA Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus Author

DOI:

https://doi.org/10.47363/JNPR/2026(4)118

Keywords:

Bed Rest, Pressure Ulcers, Urinary Incontinence, Constipation, Rehabilitation, Physiotherapy, Pharmacokinetics, Geriatric Pharmacotherapy, Hypodynamia, Frailty, Cognitive Impairment, Depression, Physical Therapy, Therapeutic Exercise, Kinesiotherapy, Early Mobilization, Aging, Pharmacodynamics, Malabsorption, Geriatric Syndromes, Multidisciplinary Care, Social Rehabilitation, Occupational Therapy, Electrophoresis, Galvanization, Ultraviolet Therapy, Decubitus Ulcers, Elderly, Senile Age, Comorbidity

Abstract

Aging is a natural process characterized by impaired neurohumoral regulation, altered receptor sensitivity, and weakened homeostasis mechanisms. These fundamental shifts at the systemic, organ, and cellular levels determine the particular vulnerability of elderly and senile patients to external and internal damaging factors.

One of the most powerful and clinically underestimated pathogenetic triggers in geriatrics is prolonged immobilization forced bed rest. Age-related increased sensitivity to physical inactivity and accelerated aging of physiological systems lead to the rapid development of severe complications: hypostatic pneumonia, thromboembolism, muscle atrophy, contractures, osteoporosis and mental disorders.

Specific syndromes associated with prolonged bed rest deserve special attention: bedsores, urinary and fecal incontinence and constipation. These conditions, perceived as inevitable manifestations of old age, are treatable in most cases with proper diagnosis, adequate care, and comprehensive therapy. A key role in the prevention and treatment of such disorders lies not only in medication but also in non-drug approaches, such as therapeutic exercise, massage, dietary therapy, and psychosocial rehabilitation. The effectiveness of treatment is largely determined by the timeliness of initiation, as well as adherence to the principles of gradualism and caution when prescribing physical therapy and balneological procedures.

Author Biographies

  • Bon LI, Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus

    Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus

  • Znavets PA, Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus

    Associative Professor, Candidate of Biological Science, Grodno State Medical University, Belarus

Downloads

Published

2026-07-22