Resolution of Severe Neonatal Brain Injury Following Biophoton Generator Exposure: A Case Report

Authors

  • Jessica Morris First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA Author
  • Helen Y Gu First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA Author
  • James Z Liu First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA Author

DOI:

https://doi.org/10.47363/JNRRR/2025(7)236

Keywords:

Neonatal Hypoxic-Ischemic Encephalopathy (HIE), Biophoton Generator, Photobiomodulation (PBM), Brain Injury, Neuroregeneration

Abstract

Background: Neonatal hypoxic-ischemic encephalopathy (HIE) due to perinatal hypoxia carries high risk of permanent neurological injury. Therapeutic hypothermia offers partial protection; complementary regenerative therapies are needed.

Case Presentation: We report an infant with confirmed severe brain injury due to birth trauma resulting in two skull fractures and a hematoma. Despite standard management, neurological recovery was minimal over two weeks. A biophoton generator device emitting non-heating photons (500–1000 nm) was introduced adjunctively, with daily exposure over several months. Within days, the infant showed improvement in sleep, soothability, and alertness. Follow-up showed sustained normalization of neurological function.

Conclusion: This case illustrates a striking association between biophoton exposure and neurological recovery in a neonate with severe brain injury. Though causality cannot be confirmed from a single case, the result supports further controlled investigation of biophoton generator exposure in neonatal neuroprotection.

Author Biographies

  • Jessica Morris, First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA

    First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA 

  • Helen Y Gu, First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA

    First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA 

  • James Z Liu, First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA

    First Institute of All Medicines, 1000 Uniqema Blvd, New Castle, DE 19720, USA 

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Published

2025-10-28

Issue

Vol. 7 No. 10 (2025): Volume 7 Issue 10

Section

Articles