Intensity Modulated Radiotherapy in the Complex Treatment of High-Risk Wilms’ Blastemal Tumor with Thrombosis in the Inferior Vena Cava - A Clinical Case from Our Practice

Abstract

Nephroblastoma is a malignant tumor that is diagnosed in children under 5 years of age. Complex treatment is required, including chemotherapy, surgery and, if necessary, local abdominal radiotherapy. The high-risk group with diffuse anaplastic or blastemal nephroblastoma after completion of chemotherapy (Ch) requires careful consideration of the timing of surgical intervention and the necessary postoperative radiotherapy.

We present this a child with high-risk blastematal type nephroblastoma with thrombosis in the inferior vena cava to emphasize how important and significant it is to carry out all components in the complex treatment, namely preoperative chemotherapy, surgical treatment, postoperative local radiotherapy, postoperative chemotherapy, and in the case of pulmonary metastases, if possible, their surgical removal and the conduct of radiotherapy to both lungs.