Plummer-Vinson Syndrome

Abstract

Plummer-Vinson syndrome is a classical triad of dysphagia, iron-deficiency anemia and esophageal webs, Plummer-Vinson or Paterson-Kelly syndrome occurs. There is no exact data on the epidemiology of the condition; the syndrome is extremely rare. Most of the patients are middle-aged white women, but the syndrome has also been identified in children and adolescents in the fourth to seventh decades of life. Over the years, dysphagia is typically painless and sporadic or incremental, restricted to solids and often related to weight loss. The association with upper alimentary tract cancers is one of the most significant clinical aspects of Plummer-Vinson syndrome. Etiopathogenesis is unknown due to Plummer-Vinson syndrome.