In-Vivo Antimicrobial Activities of Calotropis Procera (Linn) UsingExperimental Animals

Authors

  • Asoso OS School of Chemistry and Bioscience University of Bradford, United Kingdom Author
  • Oladunmoye MK Department of Microbiology, Federal University of Technology, Akure, Nigeria Author
  • Ogundare AO Department of Microbiology, Federal University of Technology, Akure, Nigeri Author

DOI:

https://doi.org/10.47363/JBBR/2023(5)158

Keywords:

Acute Toxicity, Rats, Weight, ALP, ALT, AST, Calotropis Procera

Abstract

Indigenous medicine comprises of knowledge systems that developed over subsequent years within different societies before the period of modern medicine. This work investigated on the in-vivo antimicrobial activities of the extracts (solvent used in this study are acetone, ethanol, aqueous and methanol) of stem and leaf of Calotropis procera using experimental animal (albino rats), whereby haematological and biochemical analyses were
determined using standard methods. Based on the result in this study, there was no death recorded but there was a mild toxicity effects on the liver, kidney, stomach and heart of the animals at 1000-3000 mg/kg of the rats in this research.

Author Biographies

  • Asoso OS, School of Chemistry and Bioscience University of Bradford, United Kingdom

    School of Chemistry and Bioscience University of Bradford, United Kingdom 

  • Oladunmoye MK, Department of Microbiology, Federal University of Technology, Akure, Nigeria

    Department of Microbiology, Federal University of Technology, Akure, Nigeria

  • Ogundare AO, Department of Microbiology, Federal University of Technology, Akure, Nigeri

    Department of Microbiology, Federal University of Technology, Akure, Nigeri

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Published

2023-04-10

Issue

Vol. 5 No. 2 (2023): Volume 5, Issue 2

Section

Articles