Treatment Protocols For Isolated Asthenospermia Among A Group of Patients Scheduled for an Intrauterine Insemination (IUI) Procedure: Results of a Prospective Study

Abstract

Intrauterine Insemination (IUI) is a largely used, also debated, technique. We tried to standardize a treatment protocol before IUI, to obtain an increase in 
motile sperm, expressed as Total Motile Sperm Cell (TMSC) with the aim of avoiding overtreatment in “large amount of spermatozoa” patients. 

A group of 97 patients was enrolled for a prospective study and underwent the assumption of the dietary supplement based on 100 mg ORISOD, 11 mg 
Extremely (SOD=154 IU), 50 mg lipoic acid, 30 mg glutathione, 1.5 mg zinc, 36 mg niacin, 25 mg riboflavin, 9.5 mg vitamin B6, 400 mcg folic acid, 33 mcg 
vitamin B12 for 90 day, with encouraging results. An increase in TMSC was detected in 77 patients with a.statistical significance (TMSC average increase 
from 10.7 to 15.2). Even considering this study a preliminary one, our results give a relevant contribution in a field that lack strong evidences and requires 
more randomized controlled trails (RCT).