Study of the Effect of Nanotechnology Drugs (mcs-b)on the Aggregation of Human Blood Platelets

Authors

  • Andrey N Belousov Laboratory of Applied Nanotechnology of Belousov, Department Anesthesiology, Intensive Care, Transfusiology and Hematology Kharkov Medical Academy of Postgraduate Education, Ukraine Author

DOI:

https://doi.org/10.47363/JNSRR/2019(1)102

Keywords:

Platelets, Functional, Mcs-B Nanoparticles, Saline Solution, Aggregation Rate, Aggregation Index

Abstract

This scientific article is devoted to the study of the effect of magnetite nanoparticles (MCS-B brand) on the functional platelets activity of human. 0.9% NaCl was used as a control. The results of the study showed that the use
of NaCl saline solution shifts the colloidal suspension equilibrium of platelets towards a significant (P<0.001) increase in the rate and index of their aggregation. For the first time, the effect of 0.9% NaCl on function of
platelets makes us reconsider the concept of safety of infusion solutions in patients with initial signs of platelet disorders hemostasis. On the contrary, the use of MCS-B nanoparticles significantly revealed (P<0.05) an increase in the stability of colloidal suspension of platelets. This is an important pathogenetic factor which affects the occurrence of correction of hemostasis in conditions of blood clotting disorders.

Author Biography

  • Andrey N Belousov, Laboratory of Applied Nanotechnology of Belousov, Department Anesthesiology, Intensive Care, Transfusiology and Hematology Kharkov Medical Academy of Postgraduate Education, Ukraine

    Laboratory of Applied Nanotechnology of Belousov, Department Anesthesiology, Intensive Care, Transfusiology and
    Hematology Kharkov Medical Academy of Postgraduate Education, Ukraine

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Published

2019-12-29

Issue

Vol. 1 No. 1 (2019): Volume 1 Issue 1

Section

Articles